Symmetrical lupoid onychodystrophy (SLO) is characterized by the progressive destruction and sometimes complete loss of the claws. This disease is more frequent in Rhodesian Ridgebacks than in other breeds, indicating that genetic risk factors might predispose some dogs to get this disease. We would like to further investigate the genetic risk factors for SLO in the Rhodesian Ridgeback. Our aim is the development of a genetic test, which is specifically suited for the Rhodesian Ridgeback breed. For the research we need EDTA blood samples from affected dogs, ideally together with their parents and siblings. We therefore ask breeders and owners to donate samples for our research.