Canine Ectodermal Dysplasia (CED) in Chinese Crested, Mexican and Peruvian Hairless Dogs


Hairless dogs such as Chinese crested dogs are very old breeds. Statues from Mexican hairless dogs have been dated to 1700 BC. We discovered that a variant in the FOXI3 gene causes the hairlessness. This illustrates how the existing variety of different dog breeds can facilitate important discoveries in developmental biology and biomedical research.